Polsky Center for Entrepreneurship and Innovation at the University of Chicago Unclaimed
Chicago, Illinois, United States
University of Chicago hub that fuels startups and research commercialization through mentorship, programs, and industry connections.
The Polsky Center for Entrepreneurship and Innovation at the University of Chicago accelerates the translation of research and ideas into startups and real-world impact. It serves University of Chicago students, faculty, alumni, and external small businesses by providing education, mentorship, and a suite of programs designed to help create startups and commercialize technologies. The center orchestrates technology licensing, access to capital and mentorship, and industry partnerships, and supports entrepreneurship education, events, and accelerator initiatives that connect researchers with investors and partners to move discoveries toward market.
To empower University of Chicago researchers, students, faculty, alumni, and partners to turn ideas into impactful ventures by providing education, mentorship, and access to resources and collaborations.
What we offer
New Venture Challenge
Accelerates student ventures, generating billions in funding and value.
polsky.uchicago.edu/programs-events/new-venture-challenge/Build and Launch Accelerators
Intensive support for students to develop and fund their entrepreneurial ventures.
polsky.uchicago.edu/programs-events/polsky-accelerator/Polsky Deep Tech Ventures
Accelerates deep tech startups with specialized training and funding.
polsky.uchicago.edu/types/deep-tech-ventures/Polsky Exchange
Empowers entrepreneurs with workspace, mentorship, and extensive programming.
polsky.uchicago.edu/polsky-exchange/UChicago Science Incubator
Accelerates early-stage science startups with advanced facilities and experienced guidance.
polsky.uchicago.edu/uchicago-science-incubator/Technology Licensing & Transfer (Polsky Tech Commercialization)
Facilitates commercialization of inventions from research at UChicago through licensing and partnerships.
polsky.uchicago.edu/tech-commercialization/Polsky On Demand
Access a variety of educational workshops and training at your convenience.
polsky.uchicago.edu/polsky-on-demand/Entrepreneurship Essentials (E2): Scaling with AI
Learn to utilize AI in business workflows for competitive advantage.
polsky.uchicago.edu/event/entrepreneurship-essentials-e2-scaling-with-ai-led-by-phil-leslie/Entrepreneurship Through Acquisition (ETA) Workshop
Gain resilience and practical strategies for operating acquired businesses from industry leaders.
polsky.uchicago.edu/event/entrepreneurship-through-acquisition-eta-workshop-operator-grit-overcoming-adversity/Investing Essentials: Lessons from Failure
Gain valuable insights on applying emotional intelligence to investing careers.
polsky.uchicago.edu/event/investing-essentials-lessons-from-failure/Capital Access: Mona Ventures
Access tailored insights into capital funding for small businesses from experts.
polsky.uchicago.edu/event/polsky-exchange-capital-access-mona-ventures/Who do we serve
University-Affiliated Startups
University-affiliated students and faculty building ventures seeking education and funding.
University Research Spinouts
University-origin deep-tech startups seeking licensing, funding, and strategic partnerships.
Local Entrepreneurs And Small Businesses
Local entrepreneurs seeking mentorship, programs and workspace.
Market segments
Startup accelerators and competitions
Programs that provide intensive coaching, mentorship, structured tracks, and funding outcomes to accelerate student and early-stage ventures toward market traction.
Entrepreneurship education and training
Workshops, courses, and on-demand learning focused on founder skills, investor readiness, sector-specific operational capabilities (including AI), and career pathways in entrepreneurship.
Technology transfer and commercialization
Capabilities that manage invention disclosure, licensing, industry partnership formation, and commercialization pathways to move university research into licensed products or startups.
Early-stage capital access and investor programming
Events and programming that connect founders with capital providers, teach fundraising best practices, and prepare teams to make effective investor asks.
Lab facilities and deep tech incubation
Physical infrastructure, wet lab space, and domain-focused incubation that support life sciences, quantum, clean energy, and data science ventures with equipment, management expertise, and collaborative facilities.
More information about our offering
New Venture Challenge
The New Venture Challenge is Polsky Center’s top-ranked accelerator program with five tracks designed to accelerate student ventures. It has graduated over 300 active companies that have raised more than $2.3 billion in funding and generated more than $15.4 billion in value.
- Raise Funding EfficientlyThe program enables startups to leverage resources and mentorship for effective fundraising, connecting them with investors and opportunities crucial for growth.
- Join a Robust Alumni NetworkParticipating in the NVC integrates startups into a network of successful alumni who have navigated similar challenges, fostering collaboration and support.
- Create Significant Market ImpactStartups graduating from the NVC have demonstrated exceptional market value, contributing positively to the economy and setting benchmarks for success.
- Gain Expert GuidanceParticipants benefit from the insights of seasoned entrepreneurs and experts, providing critical guidance that enhances business strategies and execution.
- Tailored Pathways for VenturesThe program offers distinct tracks catering to various business types, allowing teams to choose the pathway that best matches their market strategy and needs.
Build and Launch Accelerators
The Build and Launch accelerators provide students the opportunity to work intensively on their ventures in a collaborative environment with access to coaching, programming, and funding.
- Secure Funding To Grow VenturesSelected teams gain access to funds needed to advance their projects, allowing them to focus on growth and expansion without financial burden.
- Enhance Skills With Expert CoachingParticipants receive expert coaching to strengthen their entrepreneurial skills, navigate challenges, and develop their business ideas effectively.
- Collaborate With Peers And ExpertsTeams work alongside peers and advisors, fostering a collaborative atmosphere that encourages knowledge sharing and innovation.
Polsky Deep Tech Ventures
Polsky Deep Tech Ventures integrates Chicago Booth’s entrepreneurial training with deep foundational scientific research, offering domain-specific accelerators in addition to startup services, education, and funding to move discoveries toward market.
- Leverage Booth’s ExpertiseHarnessing Chicago Booth's resources enhances entrepreneurial training vital for startups.
- Provide Specialized SupportFacilitating tailored support ensures startups receive focused guidance in their technical fields.
- Access Comprehensive ResourcesOffering a broad range of resources empowers startups to scale effectively and efficiently.
- Secure Early-Stage CapitalProviding avenues for funding stimulates startup growth and market entry.
- Connect With Industry LeadersBridging startups with established industry leaders fosters innovation and investment opportunities.
- Enhance Entrepreneurial SkillsWorkshops aim to enhance skills critical for success in the tech startup landscape.
Polsky Exchange
Polsky Exchange is a member-driven hub offering workspace access, more than 450 annual programs and workshops, and mentorship from over 100 specialists. It also houses a Small Business Development Center providing no-cost, one-on-one confidential business advice to entrepreneurs and business owners.
- Leverage Expert MentorshipMembers receive one-on-one support from experienced mentors, assisting them in navigating the challenges of entrepreneurship.
- Access Tailored Business AdviceThe center aids both pre-venture entrepreneurs and established business owners with strategic advice and support.
- Participate in Dynamic LearningMembers can attend workshops to enhance their skills, gain insights, and connect with fellow entrepreneurs.
- Utilize Collaborative WorkspaceMembers enjoy a professional environment to develop their ideas and business ventures, with resources available onsite.
UChicago Science Incubator
The UChicago Science Incubator provides early-stage life sciences, quantum, clean energy, and data science startups with access to state-of-the-art facilities and amenities, wet lab space and equipment, and seasoned management expertise. Located in Hyde Park Labs, it brings together startups, researchers, and industry experts.
- Provides Expert GuidanceExpert management support assists startups in navigating early-stage challenges.
- Offers Advanced FacilitiesAccess to cutting-edge equipment and support services enhances startup development.
- Access to Wet Lab FacilitiesEssential resources for life sciences startups to conduct vital experiments and research.
- Situated at Hyde Park LabsProximity to the University of Chicago’s campus fosters collaboration with researchers and faculty.
- Fosters Collaborative InnovationEncourages partnerships that enhance innovation and commercial viability of technologies.
Technology Licensing & Transfer (Polsky Tech Commercialization)
Polsky Center’s Tech Transfer Office manages technology licensing and commercialization, serving as the central resource for transforming discoveries into products, services, and ventures.
- Access Resources For InventionsThe initial step for researchers to gain support in patenting and commercializing their discoveries.
- Transform Research Into Market-Ready SolutionsAllows companies to leverage University-developed technologies to create impactful products.
- Catalyze Ideas Into ImpactFosters collaborations between researchers and businesses to accelerate the development and market entry of new technologies.
- Explore Innovation PortfoliosHighlights successful UChicago startups and technological innovations, connecting them with potential partners.
- Secure Investment For StartupsProvides financial support to early-stage ventures based on UChicago research and innovations.
Polsky On Demand
Polsky On Demand is an online portal of workshops and trainings that can be accessed on demand.
- Access Workshops AnytimePolsky On Demand provides users with flexible access to a diverse set of educational resources, allowing them to engage in learning at their own pace and schedule.
Entrepreneurship Essentials (E2): Scaling with AI
Entrepreneurship Essentials E2: Scaling with AI is a Polsky Center workshop exploring how to set up autonomous AI agents that plan, decide, and execute real business workflows, turning AI from a thought partner into an operator.
- Transform AI FunctionalityThis feature enables businesses to shift AI's role from merely providing insights to actively participating in decision-making and operational tasks.
- Implement AI AgentsParticipants will learn the necessary steps to deploy AI systems capable of autonomously managing business tasks, facilitating increased efficiency and effectiveness.
- Hands-on LearningParticipants engage in interactive exercises that reinforce the application of AI strategies in business, ensuring effective skill acquisition.
- Flexible Attendance OptionsThis feature provides attendees with the option to participate in-person or virtually, accommodating various preferences and needs.
Entrepreneurship Through Acquisition (ETA) Workshop
Entrepreneurship Through Acquisition ETA Workshop focuses on resilience and the mindset needed to operate acquired businesses, with insights from industry leaders and opportunities for networking.
- Develop Resilience SkillsThe workshop emphasizes the importance of resilience, equipping participants with the mindset needed to navigate challenges in entrepreneurship.
- Gain Valuable Industry InsightsParticipants learn directly from experienced industry leaders who share their knowledge about overcoming challenges in business operations.
- Connect With Peers And ExpertsThe workshop fosters connections, allowing participants to expand their professional network and collaborate with peers and industry experts.
Investing Essentials: Lessons from Failure
Investing Essentials: Lessons from Failure is a Polsky Center workshop focused on emotional intelligence, guiding participants to connect personal life lessons with strategies for building a successful career in investing.
- Enhance Your Emotional Intelligence SkillsParticipants will learn how emotional intelligence plays a critical role in investment decision-making and how to apply it effectively.
- Connect Life Lessons To Your CareerThis feature emphasizes how personal experiences and lessons learned can inform and enhance one's approach to a career in investing.
Capital Access: Mona Ventures
Capital Access: Mona Ventures is a Polsky Center event series featuring capital providers and guidance on accessing forms of capital, including what makes a successful ask and examples of success stories.
- Learn Effective Ways To AskGain insights on structuring your capital ask, ensuring clarity and impact to attract funding.
- Gain Insights From Real ScenariosExplore real-world examples of successful capital access and how they achieved their goals to learn practical approaches.
- Understand Funding OptionsLearn about various funding sources available for businesses, including grants, loans, and angel investments.
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