Life Science Angels

Access pooled early-stage life science investment alongside sector-focused investors, with due diligence and ongoing company guidance.

Explore life science investment opportunities, learn from experienced peers, and participate in LSA’s investor community and activities.

Gain practical life science investing experience, develop entrepreneurial and analytical skills, and connect with experienced mentors and peers.

Gives sponsor organizations access to LSA investment activity, participation opportunities, member benefits, and visibility across LSA events and materials.

Early-stage life science investment

Life Science Angels invests in early-stage U.S. life science companies advancing healthcare discovery and delivery, including therapeutics, diagnostics, medical devices, digital health, and life science tools. Opportunities proceed through pre-screening, member presentations, and team-based due diligence. Participating members pool their investments through an LLC, allowing LSA to provide a company with one check and one set of investment paperwork. LSA prefers active investments, with a representative potentially serving as a board member or observer, or providing strategic or operational advice. The organization also monitors portfolio company progress and commonly participates in follow-on fundraises.

• Evaluate Opportunities In Stages
  Companies are assessed through multiple review stages, while members and fellows with relevant expertise can investigate business, market, technology, intellectual property, and financial considerations.
• Connect With Life Science Investors
  Companies in life science fields can seek investment from a group focused exclusively on the sector and spanning multiple life science verticals.
• Receive One Pooled Investment
  The company works with LSA as a single investor for the pooled investment, with one check and one set of investment paperwork rather than separate documents for individual members.
• Meet LSA Investment Criteria
  Companies can assess whether they meet LSA’s stated requirements before applying, including U.S. corporate structure, U.S.-controlled intellectual property, an eligible referral, and a complete application.
• Access Strategic And Operational Guidance
  Portfolio companies may receive investor involvement through board representation, board observation, or other strategic or operational advice.
• Maintain Investor Progress Updates
  Regular company updates and ongoing contact between LSA representatives and management help investors stay informed about portfolio company progress.
• Access Follow-On Funding Participation
  Portfolio companies may have opportunities to seek continued investment from LSA members in later fundraising rounds.
• Build Investor Connections
  Companies can connect with LSA investors through ongoing interactions and may receive mentoring and contacts from members.
• Pursue Syndicated Funding
  Companies may receive an initial LSA investment within its historically stated range, with many deals syndicated by LSA or other parties to raise $3 million or more.

LSA membership

LSA membership is for U.S.-accredited angel investors interested in life sciences. Members gain access to investment opportunities, online deal materials, a network of life science investors and experts, and opportunities to participate in screening and due diligence. Membership also includes events, education sessions, investment updates, and potential follow-on investment opportunities. Members may invest through an LSA LLC or, with affiliate membership, in opportunities outside the LSA LLC. The 2026 membership options are individual, couples/families, and affiliate; memberships are valid for one year after onboarding.

Category: Professional Networking Communities

• Explore Life Science Investment Deals
  Review investment opportunities, company applications, supporting materials, and member comments through LSA’s online tools, and hear company pitches at member meetings.
• Connect With Life Science Investors
  Build personal and professional connections with LSA members and other participants in the life science investment community.
• Contribute Expertise To Deal Evaluation
  Take part in evaluating investment opportunities alongside members and fellows with relevant expertise, and learn from their due diligence and investment experience.
• Consider Follow-On Investment Opportunities
  Review potential investments in portfolio companies that have progressed against milestones. Opportunities for members may depend on allocations to existing investors.
• Invest Through A Pooled LLC
  For investments made through an LSA LLC, members invest through a pooled structure, and LSA handles a shared set of investment documents for the company and prepares annual K-1 forms.
• Monitor Portfolio Company Progress
  Benefit from LSA’s efforts to maintain contact with portfolio company management, monitor company progress, and support engagement between investors and management.
• Learn And Connect At Member Events
  Participate in investment meetings, industry discussions, educational sessions, and social gatherings that support learning and connections across the LSA community.
• Receive Portfolio Company Updates
  Receive emailed progress reports for investments you hold, when portfolio companies provide them to LSA.
• Choose A Membership Structure
  Select an individual, couples/families, or affiliate membership structure. The options differ in who joins and whether investments are made through the LSA LLC.
• Access Relevant Angel Investing Events
  Find out about relevant events beyond LSA and, when available, receive discounted or complimentary registration or invitations to events not generally open to the public.
• Build Investment Knowledge
  Attend sessions on investment topics such as valuation, term sheets, portfolio building, and tax provisions, while consulting a tax advisor for tax advice.

LSA Investment Fellows Program

A six-month or one-year fellowship for graduate-level students, postdocs, medical trainees, and early-career professionals interested in life science innovation, entrepreneurship, and investing. Fellows receive training in investment analysis, due diligence, deal flow management, business development, and investor-entrepreneur relations, while contributing to deal screening and company investigations. They work with LSA members and the Executive Director, attend screening meetings and events, and may be assigned to the Bio/Genomics or Device/Digital Committee based on their expertise. Fellows should plan for at least 10 hours per week. Program schedules vary, and openings may be available outside the usual January and July start times.

• Build Investment Analysis Skills
  Develop practical knowledge across investment analysis and due diligence, as well as deal flow management, business development, and investor-entrepreneur relations.
• Evaluate Life Science Investment Opportunities
  Contribute to the review of investment opportunities through screening, due diligence, and clinical and market investigations, working with LSA staff and deal leads.
• Guide Entrepreneurs Through The Investment Process
  Build direct experience supporting applicants by responding to company questions and coaching entrepreneurs as they proceed through LSA's investment process.
• Develop Entrepreneurial And Investing Skills
  Practice presentation skills and build familiarity with investment criteria, valuation, term sheets, and evaluating pitches.
• Explore Life Science Industry Topics
  Broaden understanding of life science innovation through exposure to intellectual property, FDA regulations, strategic partnerships, and healthcare models.
• Learn From Experienced Life Science Mentors
  Connect with domain experts from entrepreneurial, executive, scientific, clinical, and investment backgrounds.
• Participate In Committees And Industry Events
  Engage with LSA screening committees, seminars, and networking events, and help coordinate investor involvement in external trade shows, demo days, and mentorship events.
• Connect With Fellow Life Science Professionals
  Work alongside peers who share an interest in life science innovation, industry, and entrepreneurship.
• Choose A Suitable Fellowship Term
  Program terms are designed for six months or one year, with schedules that vary and potential openings outside the usual January and July start times.
• Attend LSA Events Without Membership Fees
  Participate in LSA events without paying membership fees; access to all LSA events is complimentary.

LSA sponsorship

Life Science Angels offers an annual sponsorship program for organizations that endorse its mission. Sponsors receive full access to deals in review and the portfolio, and designated individuals receive membership benefits. Sponsorship also offers opportunities to co-invest, discuss business opportunities with presenting companies, participate in LSA activities, and gain recognition at events and through LSA materials and its website.

• Access LSA Deals And Portfolio
  Review deals under consideration by LSA and access its portfolio.
• Extend Membership Benefits To Designees
  Provide designated individuals in the organization with LSA membership benefits through the annual sponsorship.
• Co-Invest In Presented Deals
  Participate in co-investment opportunities involving deals presented to the LSA membership.
• Explore Company Business Opportunities
  Engage with presenting companies in discussions about potential partnerships, licensing, distribution, or acquisition.
• Showcase Your Organization Across LSA Channels
  Gain visibility through logo placement at events and on meeting and promotional materials, a linked listing on the LSA sponsor webpage, and appropriate mentions at LSA events.
• Join LSA Screening Committee Meetings
  Enable one representative from the sponsor organization to participate in all LSA screening committee meetings.
• Participate In Panels And Speaking Engagements
  Take part in panel positions and speaking engagements through LSA.
• Access Available Conference Discounts
  Make use of conference discounts for members when those discounts are available.