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Flow Neuroscience

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Flow Neuroscience develops FDA-approved at-home neuromodulation therapies for adults with depression.

Overview

Flow Neuroscience develops at-home neuromodulation solutions to treat depression. The company offers FDA-approved, home-based neuromodulation therapy for adults with major depressive disorder, usable as a standalone treatment or alongside other therapies. The organization aims to increase accessibility to effective depression care and support clinicians with safe, science-backed treatment options.

Mission statement

To provide accessible, evidence-based, FDA-approved neuromodulation treatments for people living with depression.

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What we offer

Flow FL-100

FDA-approved at-home treatment for depression offered as monotherapy or adjunct therapy.

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Market segments

At-home neuromodulation for major depressive disorder

Home-administered, FDA-approved neuromodulation therapy for adults with moderate to severe major depressive disorder that can be used as monotherapy or adjunctive treatment to expand access to evidence-based care.

Products: Flow FL-100

Prescription neuromodulation devices for clinical practice

Clinician-prescribed neuromodulation devices integrated into outpatient care pathways for depression, supported by randomized trial evidence and real-world safety data to inform treatment planning.

Products: Flow FL-100

Adjunctive treatment to antidepressant therapy

Therapies used alongside antidepressant medications to improve clinical response and reduce suicidal ideation, backed by clinical trial and real-world outcome data.

Products: Flow FL-100

Remote depression care and maintenance therapy

Remote-managed, home-based interventions for ongoing symptom management and maintenance treatment to improve continuity of care and access for adults with MDD, informed by real-world user data.

Products: Flow FL-100

More information about our offering

Flow FL-100

Flow FL-100 is an FDA-approved, home-based neuromodulation treatment for adults 18 and older with moderate to severe Major Depressive Disorder. It can be used as a monotherapy or as an adjunct to antidepressant therapy, without requiring prior medication failure. The device is designed for at-home use and supports Flow Neuroscience’s aim to broaden access to effective depression care. Evidence from a multisite, double-blind, randomized trial shows Flow FL-100 is effective when used as both a standalone treatment and an adjunct to antidepressant therapy at 10 weeks. Real-world data from over 40,000 users indicate a favorable safety profile with a low incidence of adverse reactions (4.5%).

  • Demonstrates Proven Effectiveness
    Results from a rigorous clinical trial validate the efficacy of Flow FL-100 as both a standalone treatment and when used alongside traditional antidepressants.
  • Enables At-Home Treatment
    Facilitates convenient access to depression treatment within the comfort of home, improving adherence and comfort.
  • Significantly Reduces Suicidal Ideation
    Demonstrates the potential of Flow FL-100 in providing critical support for individuals in crisis.
  • Targets Adult Population
    Specifically designed to meet the needs of adults suffering from significant depressive symptoms.
  • Offers Treatment Flexibility
    Provides a versatile treatment approach that accommodates varying patient needs and treatment histories.
  • Ensures Safety During Use
    Data suggest a minimal risk of side effects, supporting its safety for users.
  • Awareness of Upcoming Launch
    Keeps potential users informed about the anticipated timeline for accessing this innovative treatment in the U.S.

Sources

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